PATENTS

HOWARTH LAB

1. Papers, Pre-prints, Reviews

2. Patents

2026 US Patent and Trademark Office, patent filed 2025 US Patent and Trademark Office, patent filed Howarth M, Lim SYT. (Enhanced NeissLock) 2025 UK Intellectual Property Office Polypeptides and Peptide Tags Capable of Spontaneous Isopeptide Bond Formation at Low Temperature and Low pH and Uses Thereof Reading E, Hammerschmid D, Howarth M, Keeble AH. 2023 UK Intellectual Property Office 2315107.9 PDF A bivalent polypeptide scaffold and uses thereof. (SpyMask) Howarth M, Driscoll CL, Keeble AH. 2023 UK Intellectual Property Office 2313175.8 PDF Switchable polypeptide and its use for gentle affinity purification. (SpySwitch) Howarth M, Khairil Anuar I.N.A., Rahikainen R. 2021 UK Intellectual Property Office 2117283.8 PDF Polypeptides that interact with peptide tags at loops or termini and uses thereof. (DogCatcher) Howarth M, Yadav V, Ferla M. 2021 UK Intellectual Property Office 2104999.4 PDF Ligand-binding polypeptides and uses thereof. (Gastrobodies) Howarth M, Wicke N. 2021 UK Intellectual Property Office 2019817.2 PDF System for covalently linking proteins. (NeissLock) Howarth M, Scheu AHA, Lim SYT. 2020 UK Intellectual Property Office 2003683.6 PDF Viruses with modified capsid proteins. Dicks M, Howarth M, Biswas S. 2019 UK Intellectual Property Office 1915905.2 PDF Polypeptide with enhanced rate of spontaneous isopeptide bond formation with its peptide tag partner and uses thereof. (Spy003) Howarth M, Keeble A, Carella A. 2019 UK Intellectual Property Office 1903479.2 PDF Polypeptide and its use in affinity purification. (Spy&Go) Howarth M, Khairil Anuar I.N.A. 2018 UK Intellectual Property Office 1819850.7 PDF Peptide ligase and use thereof. (SnoopLigase) Howarth M, Buldun C. 2017 UK Intellectual Property Office 1705750.6 PDF Proteins and peptide tags with enhanced rate of spontaneous isopeptide bond formation and uses thereof. (Spy002) Howarth M, Keeble A. 2017 UK Intellectual Property Office 1706430.4 PDF Mutant streptavidin with improved fluorescent brightness and uses thereof. Howarth M, Jacobsen MT. 2016 UK Intellectual Property Office 1616051.7 PDF Methods and products for fusion protein synthesis Howarth M, Veggiani G, Gayet R. 2015 UK Intellectual Property Office 1509782.7, United Kingdom Patent application (described by Oxford University Innovation) Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds. Howarth M, Zakeri B. 2010, UK Intellectual Property Office 1002362.0 for PDF High Stability Streptavidin Mutant Proteins. (Traptavidin) Howarth M, Chivers C. 2009, UK Intellectual Property Office 0919102.4 PDF Controlled modification of semiconductor nanocrystals. Ting AY, Bawendi MG, Howarth M, Liu W. 2007, US Patent and Trademark Office. for PDF Monovalent Streptavidin compositions. Ting AY, Howarth M. 2006, US Patent and Trademark Office. for PDF
A writer should have the precision of a poet  and the imagination of a scientist                                      ― Nabokov
“Patents add the fuel of interest to the fire      of genius.” - Abraham Lincoln SOCIAL ADDRESS Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD UK CONTACT e: mh2186@cam.ac.uk t: 01223 334176  2026 Mark Howarth. All rights reserved.  
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